Researchers at Tel Aviv University has developed a new peptide in their lab to protect and restore nerve cell communications.
A structure called "the microtubule network" is a crucial part of our nervous system. It acts as a transportation system within nerve cells, carrying essential proteins and enabling cell-to-cell communications.
But in neurodegenerative diseases like Alzheimer's, ALS, and Parkinson's, this network breaks down, hindering motor abilities and cognitive function.
Now, ...
Researchers at Tel Aviv University has developed a new peptide in their lab to protect and restore nerve cell communications.
A structure called "the microtubule network" is a crucial part of our nervous system. It acts as a transportation system within nerve cells, carrying essential proteins and enabling cell-to-cell communications.
But in neurodegenerative diseases like Alzheimer's, ALS, and Parkinson's, this network breaks down, hindering motor abilities and cognitive function.
Now, ...
Doctors have finally found out the secret behind paralympic cyclist Tom Staniford's lack of fat in the body with researchers identifying a genetic mutation that makes it impossible for him to store fat under his skin. Researchers at University of Exeter conducted a complete genetic mapping and analysis of Staniford's DNA in order to identify the precise genetic mutation responsible for his condition. The researchers found that Staniford was one of just eight persons in the world to suffer from ...
Understanding how gastric bypass surgery changes the properties of nerve cells could lead to new treatments that produce the same results without surgery and help regulate the digestive system.
This is according to Penn State College of Medicine scientists, who have shown how surgery restores some properties of nerve cells that tell people their stomachs are full. The results may also better predict which patients will keep the weight off after surgery.Roux-en-Y gastric bypass surgery is the ...
In Vietnam and other locations, patients with central nervous system infections may well be suffering from the effects of a newly discovered virus.
This is according to a study to be published in imBio/i (Regd) , the online open-access journal of the American Society for Microbiology. Researchers have detected the virus in spinal fluid from 4 percent of 642 patients with central nervous system infections of unknown cause, and in an average of 58 percent of fecal samples from pigs and poultry, ...
Two large studies revealed that the association between aspirin use and risk of colorectal cancer was affected by mutation of the gene BRAF, with regular aspirin use associated with a lower risk of BRAF-wild-type colorectal cancer but not with risk of BRAF-mutated cancer. The findings found in the June 26 issue of iJAMA/i suggest that BRAF-mutant colon tumor cells may be less sensitive to the effect of aspirin.
Colorectal cancer is a leading cause of cancer-related death worldwide. Randomized ...
A gene known as FAM190A plays an important role in the regulation of the normal cell division process, known as mitosis, and mutations in the gene could be responsible for the commonly found chromosomal instability in cancer, a new study by Johns Hopkins researchers reveals.
In laboratory studies of cells, investigators found that knocking down expression of FAM190A disrupts mitosis. In three pancreatic cancer-cell lines and a standard human-cell line engineered to be deficient in FAM190A, researchers ...
For the first time, a receptor mutation that blocks estrogen's action has been discovered in a young woman.
The 18-year-old wasn't experiencing breast development or menstruation, classic symptoms of too little estrogen, the usual cause of delayed puberty. Subsequent studies revealed instead sky-high levels of the sex hormone in her blood, said Dr. Lawrence C. Layman, Chief of the Section of Reproductive Endocrinology, Infertility and Genetics at the Medical College of Georgia at Georgia Regents University....
Genetically-engineered mice that have artificial human chromosomes in every cell of their bodies were developed by scientists.
Researchers were able to create a human artificial chromosome in the lab from chemical building blocks, the Independent reported.
According to scientists, a synthetic yeast that has man-made chromosomes could eventually be used as a platform for making new kinds of biological materials, like antibiotics or vaccines, while human artificial chromosomes can be used ...
The electrical activity of the brain generated by scalp surface is measured by a test called electroencephalography.
Proper classification of electroencephalography data is the main task in electroencephalography based brain computer interface. Brain-computer interface is a communication system that connects the brain with computer (or other devices) but is not dependent on the normal output of the brain (i.e., peripheral nerve and muscle). Such interface transforms neural activities into signals ...
A key piece in the puzzle of how BRCA1 gene mutations specifically predispose women to breast and ovarian cancers was solved by scientists led by Drs. Mona Gauthier and Tak Mak at The Campbell Family Institute for Breast Cancer Research at the Princess Margaret Cancer Centre.
The answer, says Dr. Mak in research published today in the iJournal of Experimental Medicine/i, is found in the way estrogen rushes in to "rescue" cells whose healthy functioning has been altered by oxidative stress, ...
In a major breakthrough that could lead to potential treatment for Down's syndrome, a team of American gene scientists claimed that they have found a way through which they were able to switch off the rouge chromosome responsible for the condition in lab-dish cells.
The breakthrough opens up the tantalising goal of therapy for Down's, they said, cautioning that years of work lie ahead before this aim is reached -- if, in fact, it is attainable.
Down's syndrome is the world's leading genetically ...
People who are carrying a genetic mutation that causes a condition known as ARVD/C should avoid vigorous exercise, a new study published in the Journal of the American College of Cardiology reveals. ARVD/C is a condition where the genetic mutation causes heart cells to beat irregularly, also known as arrhythmia, and could be potentially fatal as the blood is not able to flow properly throughout the body. Researchers led by Dr Cynthia James at Johns Hopkins observed 87 people suffering from ARVD/C ...
Alcohol consumption during pregnancy has negative effects on fetal central nervous system, says study.
Maternal alcohol consumption prior to and during pregnancy significantly affects cognitive functions in offspring, which may be related to changes in cyclin-dependent kinase 5 because it is associated with modulation of synaptic plasticity and impaired learning and memory.
Prof. Ruiling Zhang and team from Xinxiang Medical University explored the correlation between cyclin-dependent ...
At Columbia University Medical Center (CUMC), researchers and collaborators have identified a genetic mutation that causes congenital malformations of the kidney and urinary tract.
This is a common form of birth defect and the most common cause of kidney failure in children. It is the first time that a specific genetic mutation has been linked to a non-syndromic form of urinary tract malformation. The findings were published in the July 17 online issue of the iNew England Journal of Medicine/i....
New analysis reveals that the X chromosome, which was long perceived as the "female" counterpart to the male-associated Y chromosome, actually plays a specialized role in sperm production.
This surprising finding, reported by Whitehead Institute scientists in a paper published online this week in the journal Nature Genetics, is paired with another unexpected outcome: despite its reputation as the most stable chromosome of the genome, the X has actually been undergoing relatively swift change....
Shedding light on how cells regenerate protective sheaths around nerve fibres in the brain, could be the potential breakthrough, researchers are seeking, to develop a treatment to repair nerve damage in multiple sclerosis patients is a new study.
These sheaths, made up of a substance called myelin, are critical for the quick transmission of nerve signals, enabling vision, sensation and movement, but break down in patients with multiple sclerosis (MS).
The study, by the Universities of Edinburgh ...
Digital versions of a standard molecular biology tool to detect a common tumor-associated mutation in the cerebrospinal fluid (CSF) of patients with brain tumors were used by Massachusetts General Hospital (MGH) researchers and their colleagues. In their report being published in the open-access journal iMolecular Therapy - Nucleic Acids/i, the investigators describe using advanced forms of the gene-amplification technology polymerase chain reaction (PCR) to analyze bits of RNA carried in membrane-covered ...
Dissecting the recurrent laryngeal nerve during thyroid surgery is clinically significant for preventing nerve injury, according to a retrospective clinical controlled study conducted by researchers at Xinhua Hospital, Shanghai Jiao Tong University School of Medicine.
To determine the value of dissecting the recurrent laryngeal nerve during thyroid surgery with respect to preventing recurrent laryngeal nerve injury, this study retrospectively analyzed clinical data from 5 344 patients undergoing thyroidectomy....
About half of a small group of patients with fibromyalgia was found to have damage to nerve fibers in their skin and other evidence of a disease called small-fiber polyneuropathy (SFPN).
Fibromyalgia is a common syndrome that causes chronic pain and other symptoms. Unlike fibromyalgia, which has had no known causes and few effective treatments, SFPN has a clear pathology and is known to be caused by specific medical conditions, some of which can be treated and sometimes cured. The study from ...
